Abacavir D5 is a deuterated form of the antiretroviral drug Abacavir. Abacavir is used in combination with other antiretroviral medications to treat HIV infection. It works by inhibiting the reverse transcriptase enzyme of the virus, which is necessary for the virus to replicate. Abacavir D5 is an isotopically labeled form of Abacavir, containing five deuterium atoms. This labeling is useful in pharmacokinetic studies, as it allows for the tracking of the drug's metabolism and distribution in the body. Additionally, it can help to identify drug interactions and potential side effects.

The chemical structure of Abacavir D5 is identical to that of Abacavir, with the exception of the deuterium labeling. It has a molecular weight of 281.37 g/mol and a molecular formula of C14H16N5O4D5. It is a white to off-white powder that is soluble in water. Abacavir D5 is typically administered orally in tablet form, with a standard dose of 600mg once daily for adults. It is important to take the medication exactly as prescribed, and to continue taking it even if symptoms improve. Discontinuing the medication prematurely can lead to the development of drug-resistant HIV strains. Overall, Abacavir D5 is a useful tool in the study of Abacavir's pharmacology, and can aid in the development of more effective HIV treatments.